Thrilled to share our review paper, out today in @NatureRevGenet : "Harnessing artificial intelligence to advance CRISPR-based genome editing technologies" Full paper : 🔗 https://t.co/ZBJcgDZduY CRISPR has already changed medicine. AI is now changing CRISPR. We spent a long time mapping the full landscape of where machine learning and deep learning are having real, measurable impact across the genome editing workflow — and where the most exciting opportunities lie ahead. Here's what we cover: Guide RNA design — Deep learning models now predict on- and off-target activity for Cas9, Cas12, Cas13, and emerging systems like TnpB and IscB. We've gone from sequence heuristics to transformer-based models that generalize across organisms. Cell-type-specific generalization remains a frontier. Base and prime editing — ML models predict bystander effects, product purity, and editing efficiency from sequence context alone. For prime editing, tools like PRIDICT and DeepPE have made pegRNA design far more tractable at scale. Enzyme engineering — Protein language models (ESM, EVOLVEpro) are now guiding directed evolution of Cas proteins — expanding PAM compatibility, reducing immunogenicity, improving compactness — at a pace impossible through classical lab iteration alone. Novel enzyme discovery — Foundation models trained on metagenomics are uncovering entirely new CRISPR systems from microbial diversity: new Cas variants, TnpB systems, and eukaryotic Fanzor proteins. The search space is enormous; AI is how we navigate it. Virtual cell models — This is where I'm most excited. AI-powered virtual cells can, in principle, predict the functional consequences of any edit in any cell type — selecting targets, anticipating off-targets, modeling tissue-specific outcomes. But realizing this vision requires causally-rich, contextually diverse perturbation data. Scale of data matters as much as scale of model. Delivery — ML-guided LNP design is closing the last mile between an edit that works in a dish and one that works in a patient. Across all of this, one theme recurs: AI accelerates where data is abundant and well-structured. The field's next challenge is generating that data at the right diversity and scale. This paper was a true collaboration. Huge thanks to Tyler Thomson, Gen Li, Amy Strilchuk, @HAOTIANCUI1 , and Bowen Li — you each brought something irreplaceable to this. Special shoutout to @BowenLi_Lab for his leaderhsip in this work!

Have questions you’d like addressed during the meeting? Drop them here: https://t.co/4DXYuyzHkP

From desktop applications to national laboratory research, see what developers are building with Mojo🔥 This month's Community Meeting features GTK bindings with live GUI demos, Oak Ridge National Laboratory's GPU benchmark study comparing NVIDIA and AMD performance, and the 26.1 release including compile-time reflection and Apple Silicon GPU support. https://t.co/aral6XFkJZ

Modular has acquired @bentomlai! 🤝 10K+ orgs use BentoML for production AI, including 50+ Fortune 500 companies. We're pairing their deployment platform with MAX + Mojo's hardware optimization. BentoML stays open source (Apache 2.0), and we’re doubling down on OSS in 2026. Ask BentoML founder @chaoyu_ and @clattner_llvm anything on Feb 17 at 9:30am PT. Get all the details: https://t.co/lifotwMzR2

Join us today at 9:30 AM PT in the Modular forum for an Ask Us Anything session with @clattner_llvm and @chaoyu_ about our recent acquisition of @bentomlai! We'll answer your questions live and share our vision for the future. 🔮 https://t.co/xiWHUAFsFZ https://t.co/divCcPzlNO

Mojo in Jupyter is here 🙌 @jeremyphoward released a new Jupyter kernel that lets you run Mojo directly in notebooks. It works great on macOS, supports recent Linux versions, and is easy to install via pip or uv. Give it a try and let us know what you build! https://t.co/3AN1UooKCd #MojoLang #OpenSource #DeveloperTools

The Claude C Compiler is the first AI-generated compiler that builds complex C code, built by @AnthropicAI. Reactions ranged from dismissal as "AI nonsense" to "SW is over": both takes miss the point. As a compiler🐉 expert and experienced SW leader, I see a lot to learn: 👇 https://t.co/ywwtnDWY7E

Episode #5 of the Mojo 🔥 GPU Puzzle series is up, and it covers broadcasting! No memory duplication here. Instead, we're focusing on logical expansion of lower-dimension arrays across higher-dimension shapes. Sounds simple in theory, but matters a lot when managing 2D thread grids. Watch the episode: https://t.co/4qC2NSXah5

The multi-platform problem has a lot of potential solutions. In his talk at CODAI 2026, open source contributor Maxim Zaks proposes Mojo 🔥 as the answer, walking through compile-time generics, cross-GPU dispatch, and where MAX fits in: https://t.co/ruOtizXNSP

Our fave slide: 2026 is the year of Mojo! 1.0 and compiler open sourcing are on the horizon. 🥳 https://t.co/uKYhCEUW3o

We're heading to @NVIDIAGTC 🙌 Find us at Booth #3004, March 16-19 in San Jose, CA. Get a first look at Modular Cloud, now in early access, with DeepSeek V3.1 serving live. Plus live Mojo 🔥 GPU programming on NVIDIA Blackwell, the latest AI models in MAX, and AI-assisted kernel development. All powered by Mojo 🔥 and MAX, a simpler way to hit SOTA performance across heterogeneous hardware. Come for the GPU code, stay for the swag and a @clattner_llvm sighting 👀

GPU Puzzle #6: implement a kernel that adds 10 to each position of a vector. The solution is just 3 lines, and getting there requires understanding global thread indexing and what breaks when you skip the bounds check. 🤔 Full walkthrough in our new video: https://t.co/6f1Kg2AkqC

The Modular team just wrapped our offsite in New Orleans🐊 Whole company, lots of big ideas and we're just getting started 🙌 https://t.co/7NEpHQoXsg

Thrilled to share that I’ve joined @GoogleDeepMind to work on Gemini post-training! I feel incredibly fortunate to be cooking on this sunny island under @YiTayML's leadership, within @quocleix's broader organization. Looking forward to enjoying RL research and pushing the frontiers of Gemini alongside such a brilliant team!

Paper link: https://t.co/moEwpmLk56

Gemini 3 Deep Think is here! 😎 This model is not only super strong in math and coding (IMO gold and 3455 codeforces ELO), it is also gold standard in physics and chemistry olympiads. 😃 Also sets new records on ARC-AGI-2 and HLE. Proud to be a (core) member of the Deep Think team. 🦾😆. Feeling the AGI!

Blogpost here: https://t.co/6fNvurCOzB

Introducing Aletheia, a math research agent powered by an advanced version of Gemini Deep Think that produces publishable math research (two papers, one completely automatic and another with human-AI collaboration) and solved multiple open Erdős problems. 😀🔥 Paper link below! 👇

Today, we’re continuing to push the boundaries of AI with our release of Gemini 3.1 Pro. This updated model scores 77.1% on ARC-AGI-2, more than double the reasoning performance of its predecessor, Gemini 3 Pro. Check out the visible improvement in this side-by-side comparison, showing Gemini 3.1 Pro’s crisp animation built with pure code. Read more about today’s 3.1 Pro update: https://t.co/vABdcMSE3f

Gemini 3.1 Pro is here. Hitting 77.1% on ARC-AGI-2, it’s a step forward in core reasoning (more than 2x 3 Pro). With a more capable baseline, it’s great for super complex tasks like visualizing difficult concepts, synthesizing data into a single view, or bringing creative projects to life. We’re shipping 3.1 Pro across our consumer and developer products to bring this underlying leap in intelligence to your everyday applications right away. Rolling out now to: - Developers in preview via the Gemini API in @GoogleAIStudio - Enterprises in Vertex AI and Gemini Enterprise - Everyone through the @Geminiapp and @NotebookLM

Exciting results in AI math research! We use Aletheia agent, powered by Gemini 3 Deep Think, to tackle the FirstProof challenge. Operating completely autonomously, Aletheia successfully solved 6 out of the 10 problems. Check out the full paper for details on the methodology and expert evaluations. https://t.co/jGebqX543b

Nano Banana 2, new state of the art in image generation and editing combined with Gemini’s real-world knowledge! You can simulate 3D CAD models purely through images. From sketch to real object! https://t.co/rQoMNrica5

Everyone’s talking about Ralph Wiggum in the AI world but most people still don’t get why it matters. Autonomous loops in Claude Code are quietly changing how devs build. We broke it down step-by-step 👇 🧠 What Ralph Wiggum actually does 🔁 How autonomous loops work ⚙️ How to use it hands-off in real projects A good read if you’re building with AI, not just prompting it. Link Below!

We sat down with Kaleen Canevari - a multi-time founder and mechanical engineer - to talk about how she’s using AI coding tools to build a new platform for the Pilates world 🧘‍♀️ Kaleen’s journey is a perfect example of modern product building: •Started with early experiments using @claudeai + Xcode •Shipped quickly with @Lovable •Now building in @cursor_ai + @supabase •Uses @braingridai as a technical co-founder to plan features, break them down, and implement reliably as the product scales What we talk about: •How vibe coding helped her build without getting stuck in syntax •Her workflow for validating ideas before writing production code •Why BrainGrid helps turn product intent into clean execution •What she’s building: a hybrid digital platform for Pilates studios •The bigger vision: better Pilates language + data for personalization and measurable outcomes •The next big pain point: troubleshooting across infra and dashboards, not just code If you’re building with AI tools and want to ship faster without breaking your app, this one’s for you.