@minchoi
This story is wild… Paul used AI (ChatGPT, Gemini, and Grok) to help create a personalized mRNA cancer vaccine protocol for his dog Rosie. As a real, months-long process involving vets, genomics labs, scientists, sequencing, and AI. Here's how he did it👇 > Rosie's cancer was missed for ~11 months, then finally diagnosed after it had progressed badly > He used ChatGPT, Gemini, and Grok to rapidly learn cancer biology, treatment options, and bioinformatics workflows > Rosie first went through chemo, immunotherapy, and multiple surgeries, but better options were still needed > They sequenced Rosie's normal DNA, tumor DNA, and later tumor RNA to identify what was actually driving the cancer > AI helped design the analysis pipeline, troubleshoot tools, interpret results, and narrow the field to the most relevant targets > Earlier approaches like ligand discovery and compound matching hit legal, timing, and approval dead ends > So they pivoted to a personalized neoantigen mRNA vaccine: identify the best tumor-specific targets, then design a custom construct around them > Labs and scientists handled the real-world work: tissue processing, sequencing, vaccine manufacturing, ethics approvals, and treatment administration > The final protocol was multimodal, not just the vaccine: targeted therapy + immune support + timing/sequencing of treatment > Months later, some tumors began shrinking AI didn't do this alone. But it gave one determined person the leverage to operate more like a research team than an individual.
