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  "text": "What if AI could invent enzymes that nature hasn’t seen? 👩‍🔬🧑‍🔬\n\nIntroducing 🪩 DISCO: Diffusion for Sequence-structure CO-design\n\n14 rounds of directed evolution and over a year of wet lab work. That's what it took to engineer an enzyme for selective C(sp³)–H insertion, one of the most challenging transformations in organic chemistry.\n\nDISCO surpasses this with a single plate. No pre-specified catalytic residues, no template, no theozyme, no inverse folding, just joint diffusion over protein sequence and structure.\n\n📝 Blog: https://t.co/j9Za0JigfO\n📄 Paper: https://t.co/ficrYNBBrM\n💻 Code: https://t.co/p81sSwoaPH",
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